Symbol
Name
ID

Syt2
synaptotagmin II
MGI:99666

Phenotype annotations related to nervous system

Darker colors indicate more annotations

Human Phenotypes

Frontalis muscle weakness

Dysphagia

Difficulty walking

Easy fatigability

Bulbar palsy

Fatigable weakness

Ataxia

EEG with polyspike wave complexes

Compound muscle action potential amplitude facilitation

Decreased compound muscle action potential amplitude

Choking episodes

Intellectual disability

Central sleep apnea

Obstructive sleep apnea

Areflexia

Hyporeflexia

Tip-toe gait

Waddling gait

Motor delay

Motor polyneuropathy

Seizure

Distal sensory impairment

Disease(s) Associated with SYT2

congenital myasthenic syndrome

congenital myasthenic syndrome 7

Mouse Phenotypes		abnormal CNS synaptic transmission	abnormal excitatory postsynaptic currents	prolonged excitatory postsynaptic current rise time	abnormal inhibitory postsynaptic currents	abnormal miniature excitatory postsynaptic currents	abnormal miniature endplate potential	abnormal neurotransmitter secretion	decreased neurotransmitter release	enhanced paired-pulse facilitation
Availability	Mouse Genotype	abnormal CNS synaptic transmission	abnormal excitatory postsynaptic currents	prolonged excitatory postsynaptic current rise time	abnormal inhibitory postsynaptic currents	abnormal miniature excitatory postsynaptic currents	abnormal miniature endplate potential	abnormal neurotransmitter secretion	decreased neurotransmitter release	enhanced paired-pulse facilitation
	Syt2^m1Ingm/Syt2^m1Ingm
	Syt2^tm1Sud/Syt2^tm1Sud

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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